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All these suggest that hepatocytes may downregulate the expression of HNF4 in an injured liver, which promote the EMT of hepatocytes and contribute to the fibrosis process (100)

Despite its theoretical appeal for treating insomnia (Choi et al., 2022), especially as an age-related intervention (Xu et al., 2020), the efficacy, optimal dosing, and pharmaceutical formulations of melatonin remain under-researched, indicating a need for further scientific validation to establish its clinical utility (Poza et al., 2022)

Bone marrow-specific TGF-1 KO or the use of TGF-R1 inhibitors significantly improves liver regeneration after AILI

Haematopoietic stem cell transplantation for sickle cell disease current practice and new approaches

Resistance to ferroptosis may promote tumorigenesis and mediate tumor cell resistance to therapeutic drugs